What We Know about the H5N1 , Avian Flu Virus
From CDC
Bird Flu: What We Know So Far about H5N1 in the United States
Gain of Function Research on H5N1
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3484390/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4278543/
https://pubmed.ncbi.nlm.nih.gov/32848003/
https://vaxxter.com/h5n1-bird-flu/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7110774/
the H5N1 subtype is an RNA virus (https://en.m.wikipedia.org/wiki/RNA_virus).
It has a segmented genome
(https://en.m.wikipedia.org/wiki/Genome) of eight negative sense, single-strands of RNA (https://en.m.wikipedia.org/wiki/RNA), abbreviated as PB2, PB1, PA, HA, NP, NA, MP and NS.[citation needed (https://en.m.wikipedia.org/wiki/Wikipedia:Citation_needed)%5D
HA codes for hemagglutinin (https://en.m.wikipedia.org/wiki/Hemagglutinin), an antigenic (https://en.m.wikipedia.org/wiki/Antigen)
Hemagglutinin is a glycoprotein ( SARS-COV-2 spike is also a glycoprotein)
https://pubmed.ncbi.nlm.nih.gov/35300999/
(https://en.m.wikipedia.org/wiki/Glycoprotein) found on the surface of the influenza viruses and is responsible for binding the virus to the cell that is being infected.
NA codes for neuraminidase (https://en.m.wikipedia.org/wiki/Viral_neuraminidase), an antigenic glycosylated enzyme (https://en.m.wikipedia.org/wiki/Enzyme) found on the surface of the influenza viruses.
It facilitates the release of progeny viruses from infected cells.
[35]
The hemagglutinin (HA) and neuraminidase (NA) RNA strands specify the structure of proteins that are most medically relevant as targets for antiviral drugs and
antibodies (https://en.m.wikipedia.org/wiki/Antibody).
HA and NA are also used as the basis for the naming of the different subtypes of influenza A viruses. This is where the
H and N come from in H5N1.
Type II transmembrane serine proteases as potential target for anti-influenza drug discovery – PubMed
Serine protease
https://pubmed.ncbi.nlm.nih.gov/28870104/
Nattokinase a serine protease enzyme which degrades spike glycoproteins
https://pubmed.ncbi.nlm.nih.gov/36080170/
Nattokinase (Bac s 1), a subtilisin family serine protease, is a novel allergen contained in the traditional Japanese fermented food natto – PubMed
https://pubmed.ncbi.nlm.nih.gov/36517353/
So Nattokinase should also degrade hemagglutinin a glycoprotein like the spike protein – both from RNA viruses . Available from Amazon ,Vitacost, or vitamin store.