Ladies and Gentlemen,
Attached is an Interesting article: Hydroxychloroquine Has about 90 Percent Chance of Helping COVID-19 Patients
As you read, does the reported action of HCQ sound like ColdEze?
This AAPS article suggest that HCQ interferes with viral infection with or without zinc by preventing virus connection to human host and preventing viral RNA transfer into human cell cytoplasm.
It does not recognize or report HCQ as a zinc ionophore. Again the emphasis is placed upon the synthetic drug and not upon the critical importance of zinc as the antiviral RNA RT inhibitor nor the importance of zinc as one of the body’s essential immune regulators.
Pyrithione plus Zinc has been shown in vitro to interfere with SARS-CoV1 RNA RT and prevent further virion production and is classified as an anti-viral agent. But zinc’s importance is not emphasized. Why not?
Pyrithione plus Zinc is also effective for treating dandruff and dermatitis (anti bacterial , anti fungal). Zinc oxide is also used as a topical creme to prevent/mitigate sunburn /UV dermal burn and DNA irradiation damage.
Pyrithione is a “Zinc Ionophore”, similar in action to ColdEze which uses acetic acid/acetate as an ionophore/ligand/chelator to transports zinc to mitigate Rhinovirus infection when administered at first signs of a cold. Rhinovirus is in the family of Coronaviruses.
The medical and pharmaceutical industries need to recognize / promote the importance of zinc which is essential to human Immune regulation. However zinc needs ionophores (transporter molecules) to be transported across cell membranes into the cellular cytoplasm.
The human body uses metalloproteins, zinc Zip proteins/enzymes/ionophores to deliver zinc across various organ cell membranes for DNA:RNA synthesis. Zinc is involved in over 300 regulatory protein/enzyme reactions in the body, one being Immune response/defense.
I believe CV19 and other Coronaviruses inhibit/interfere with the body’s transport of zinc protein Ionophores and prevent zinc from crossing infected cell membranes. Zinc concentration/availability in blood serum is also an essential/critical factor in Immune response. Zinc deficiencies caused by diet, gut flora issues, inflammatory and or immunosuppressive diseases are part of the cause/effect reality associated with this pandemic.
The most logical deduction is that this virus manufacturers a proteolytic enzyme which inhibits the human zip protein from transporting zinc across organ cell membranes , thus causing zinc deficiencies and resulting in immune suppression and observed lung, heart, kidney, brain Stroke, blood vessel, cytokine storm, & Kawasaki Disease symptoms.
Hypothesis: Use Zinc + Non Protein Ionophore to treat COVID-19 patients.
Since the body’s zip proteins are critical to transporting zinc and are maybe inhibited by this virus, one possible solution is to implement /use of “non protein”ionophores Plus zinc to transport zinc across human cell membranes.
HCQ, Pyrithione, and other synthetic/man made drugs, non protein, zinc ionophores/zinc ligand/chelators are possible solutions as are natural Quercetin, Resveratrol, ECGC polyphenol flavonoid non protein, zinc ionophores to transport zinc.
Respectfully,
EJ Ledet
Product Assurance LLC
Bellingham WA
Effective Thinking 